TY - JOUR T1 - GERD: A practical approach JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 223 LP - 230 DO - 10.3949/ccjm.87a.19114 VL - 87 IS - 4 AU - Andrew Young AU - Mythri Anil Kumar AU - Prashanthi N. Thota Y1 - 2020/04/01 UR - http://www.ccjm.org/content/87/4/223.abstract N2 - Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies taken to rule out eosinophilic esophagitis. This review discusses the evidence for different medical, endoscopic, and surgical therapies and presents a management algorithm. ER -