PT  - JOURNAL ARTICLE
AU  - Stein, Evan A.
TI  - Aggressive treatment of dyslipidemia: A review of supporting evidence
DP  - 2001 Feb 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 130--142
VI  - 68
IP  - 2
4099  - http://www.ccjm.org/content/68/2/130.short
4100  - http://www.ccjm.org/content/68/2/130.full
SO  - Cleve Clin J Med2001 Feb 01; 68
AB  - Clinical trial data are now sufficient to support aggressive treatment of dyslipidemia. Cholesterol-lowering therapy is known to reduce the risk of clinical events across a wide range of lipid levels, even in patients with "normal" levels. Current data support lowering low-density lipoprotein cholesterol (LDL-C) levels at least to those recommended by the National Cholesterol Education Program, but perhaps even more aggressively in some patients. Of the available cholesterol-lowering agents, statins produce the greatest reductions in LDL-C levels and coronary events and are currently the best treatment option for most patients.