RT Journal Article SR Electronic T1 Use of cholinesterase inhibitors for treatment of Alzheimer disease JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 608 OP 616 VO 68 IS 7 A1 Hake, Ann Marie YR 2001 UL http://www.ccjm.org/content/68/7/608.abstract AB The four cholinesterase inhibitors now available for treatment of Alzheimer disease (AD) may be most beneficial, especially in the long run, if started early in the course of the disease. This paper reviews the efficacy, pharmacokinetics, metabolism, side effects, dosage, and precautions for the use of these agents, which may produce modest improvements in cognition, behavior, and the ability to perform activities of daily living.