PT - JOURNAL ARTICLE AU - James N. George AU - Sara K. Vesely TI - Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: Diagnosis and treatment DP - 2001 Oct 01 TA - Cleveland Clinic Journal of Medicine PG - 857--878 VI - 68 IP - 10 4099 - http://www.ccjm.org/content/68/10/857.short 4100 - http://www.ccjm.org/content/68/10/857.full SO - Cleve Clin J Med2001 Oct 01; 68 AB - Prompt recognition of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) and initiation of plasma exchange treatment is critical as it substantially decreases mortality. Nevertheless, death and long-term complications remain common. The recent relaxation of diagnostic criteria has dramatically increased the number of patients treated for clinically suspected TTP-HUS.