TY - JOUR T1 - Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: Diagnosis and treatment JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 857 LP - 878 VL - 68 IS - 10 AU - James N. George AU - Sara K. Vesely Y1 - 2001/10/01 UR - http://www.ccjm.org/content/68/10/857.abstract N2 - Prompt recognition of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) and initiation of plasma exchange treatment is critical as it substantially decreases mortality. Nevertheless, death and long-term complications remain common. The recent relaxation of diagnostic criteria has dramatically increased the number of patients treated for clinically suspected TTP-HUS. ER -