RT Journal Article SR Electronic T1 Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: Diagnosis and treatment JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 857 OP 878 VO 68 IS 10 A1 James N. George A1 Sara K. Vesely YR 2001 UL http://www.ccjm.org/content/68/10/857.abstract AB Prompt recognition of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) and initiation of plasma exchange treatment is critical as it substantially decreases mortality. Nevertheless, death and long-term complications remain common. The recent relaxation of diagnostic criteria has dramatically increased the number of patients treated for clinically suspected TTP-HUS.