PT - JOURNAL ARTICLE AU - Larosa, Steven P. TI - Sepsis: Menu of new approaches replaces one therapy for all DP - 2002 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 65--73 VI - 69 IP - 1 4099 - http://www.ccjm.org/content/69/1/65.short 4100 - http://www.ccjm.org/content/69/1/65.full SO - Cleve Clin J Med2002 Jan 01; 69 AB - Effective therapies for sepsis are being devised, after many failures. However, instead of a “one therapy for all” approach, management of sepsis will involve a menu of treatments, depending on the presence of inflammatory markers, the severity of disease, and other factors. This article looks at promising new therapies, including recombinant human activated protein C (rhAPC; drotrecogin alfa, Xigris), recently approved by the US Food and Drug Administration.