RT Journal Article SR Electronic T1 Thyrotoxicosis and the cardiovascular system: Subtle but serious effects JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 57 OP 63 VO 70 IS 1 A1 Roffi, Marco A1 Cattaneo, Fabio A1 Topol, Eric J. YR 2003 UL http://www.ccjm.org/content/70/1/57.abstract AB Thyrotoxicosis is associated with increased cardiovascular morbidity and mortality, primarily due to heart failure and thromboembolism. However, its signs and symptoms may be subtle and can easily be missed. Therefore, one should suspect thyrotoxicosis in patients with palpitations, exercise intolerance, dyspnea on exertion, and other cardiovascular signs.