RT Journal Article SR Electronic T1 Advances in treatment of chronic hepatitis C: ‘Pegylated’ interferons JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 155 OP 159 VO 69 IS 2 A1 Sharieff, Khavir A. A1 Duncan, David A1 Younossi, Zobair YR 2002 UL http://www.ccjm.org/content/69/2/155.abstract AB New regimens consisting of pegylated interferons plus ribavirin may produce a sustained virologic response in more than 50% of cases of chronic hepatitis C. In contrast, the combination of standard interferon alfa and ribavirin, which was the standard of care until recently, produced a sustained virologic response in 35% to 40% of cases. As the efficacy of newer regimens improves, additional steps to adequately manage their side effects and maximize adherence may become crucial.