PT  - JOURNAL ARTICLE
AU  - Frutos-Vivar, Fernando
AU  - Esteban, Andrés
TI  - When to wean from a ventilator: An evidence-based strategy
DP  - 2003 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 389--400
VI  - 70
IP  - 5
4099  - http://www.ccjm.org/content/70/5/389.short
4100  - http://www.ccjm.org/content/70/5/389.full
SO  - Cleve Clin J Med2003 May 01; 70
AB  - It is often unclear when and how to wean patients from mechanical ventilation. We have devised an evidence-based protocol in which patients undergo a 30-minute trial of spontaneous breathing with a T tube or pressure support of 7 cm H2O. Those who can tolerate the trial are extubated, while those who cannot are reconnected to mechanical ventilation but undergo another trial every day until they can be extubated. More study is needed to improve the criteria to predict successful spontaneous breathing and extubation, and to clarify the role of noninvasive ventilation to avoid reintubation.