PT  - JOURNAL ARTICLE
AU  - Rehm, Susan J.
TI  - Two new treatment options for infections due to drug-resistant gram-positive cocci
DP  - 2002 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 397--413
VI  - 69
IP  - 5
4099  - http://www.ccjm.org/content/69/5/397.short
4100  - http://www.ccjm.org/content/69/5/397.full
SO  - Cleve Clin J Med2002 May 01; 69
AB  - Gram-positive cocci, including enterococci and Staphylococcus aureus, have become the leading cause of hospital-acquired infections, and their resistance to antibiotics is increasing.Two important new drugs—quinupristin/dalfopristin (Synercid) and linezolid (Zyvox)—were designed specifically to treat infections due to drug-resistant gram-positive cocci. But their use must be tempered by their cost, toxicity, and concerns about further development of resistant strains.