PT  - JOURNAL ARTICLE
AU  - Mohannad Dugum
AU  - Robert O’shea
TI  - Hepatitis C virus: Here comes all-oral treatment
AID  - 10.3949/ccjm.81a.13155
DP  - 2014 Mar 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 159--172
VI  - 81
IP  - 3
4099  - http://www.ccjm.org/content/81/3/159.short
4100  - http://www.ccjm.org/content/81/3/159.full
SO  - Cleve Clin J Med2014 Mar 01; 81
AB  - Treatment for chronic hepatitis C virus (HCV) infection is evolving rapidly. The approval in 2013 of two new directacting antivirals—sofosbuvir (a polymerase inhibitor) and simeprevir (a second-generation protease inhibitor)— opens the door for an all-oral regimen, potentially avoiding interferon and its harsh side effects. Other direct-acting antivirals are under development.