PT - JOURNAL ARTICLE AU - Deal, Chad AU - Gideon, James TI - Recombinant human PTH 1-34 (Forteo): An anabolic drug for osteoporosis DP - 2003 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 585--601 VI - 70 IP - 7 4099 - http://www.ccjm.org/content/70/7/585.short 4100 - http://www.ccjm.org/content/70/7/585.full SO - Cleve Clin J Med2003 Jul 01; 70 AB - Forteo (teriparatide of rDNA origin), a genetically engineered fragment of parathyroid hormone, is the first of a new class of drugs to treat osteoporosis. The drug’s anabolic action increases bone turnover, stimulating osteoblasts to a greater extent than osteoclasts, and reducing both vertebral and nonvertebral fractures. However, a number of issues about its use remain unanswered.