RT Journal Article
SR Electronic
T1 Recombinant human PTH 1-34 (Forteo): An anabolic drug for osteoporosis
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 585
OP 601
VO 70
IS 7
A1 Deal, Chad
A1 Gideon, James
YR 2003
UL http://www.ccjm.org/content/70/7/585.abstract
AB Forteo (teriparatide of rDNA origin), a genetically engineered fragment of parathyroid hormone, is the first of a new class of drugs to treat osteoporosis. The drug’s anabolic action increases bone turnover, stimulating osteoblasts to a greater extent than osteoclasts, and reducing both vertebral and nonvertebral fractures. However, a number of issues about its use remain unanswered.