%0 Journal Article %A Anthony J. Furlan %T Acute stroke therapy: Beyond IV tPA %D 2002 %J Cleveland Clinic Journal of Medicine %P 730-734 %V 69 %N 9 %X Although intravenous tissue plasminogen activator (IV tPA) has been approved for treating acute ischemic stroke, it must be given within 3 hours of stroke onset and only after ruling out hemorrhagic stroke by computed tomography. Several medical centers are turning to angiography to guide intra-arterial infusion of thrombolytic agents and mechanical endovascular interventions. %U https://www.ccjm.org/content/ccjom/69/9/730.full.pdf