TY - JOUR T1 - The case for hormone replacement: New studies that should inform the debate JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 670 LP - 678 VL - 69 IS - 9 AU - Holly L. Thacker Y1 - 2002/09/01 UR - http://www.ccjm.org/content/69/9/670.abstract N2 - The Women’s Health Initiative found that the risks of hormone replacement therapy (HRT) exceeded its benefits in a large group of older postmenopausal women, but did not consider the efficacy of HRT in relieving vasomotor symptoms. Another recent study found that low-dose HRT was as effective as standard-dose HRT while causing fewer side effects. Smaller studies suggest that HRT may improve depression. HRT is not to be used for cardiovascular risk reduction. Genetic testing may point the way to more rational use of HRT. ER -