RT Journal Article SR Electronic T1 Special management challenges in hepatitis C JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP S27 OP S33 VO 70 IS 9 suppl 4 A1 Martagon, Jose A1 Gordon, Steven M. YR 2003 UL http://www.ccjm.org/content/70/9_suppl_4/S27.abstract AB Infection with hepatitis C virus (HCV) often coexists with other conditions and patient factors that complicate its management. Infection with HIV is a particularly widespread and vexing comorbidity of HCV infection, since HIV facilitates HCV transmission and renders HCV more opportunistic. This review provides a practical overview of major comorbidities and patient factors that require special management considerations in patients with HCV infection.