PT  - JOURNAL ARTICLE
AU  - Brotman, Daniel J.
AU  - Girod, John P.
TI  - The metabolic syndrome: A tug-of-war with no winner
DP  - 2002 Dec 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 990--994
VI  - 69
IP  - 12
4099  - http://www.ccjm.org/content/69/12/990.short
4100  - http://www.ccjm.org/content/69/12/990.full
SO  - Cleve Clin J Med2002 Dec 01; 69
AB  - The metabolic syndrome may be viewed as a state of insulin-counterregulatory overdrive: counterregulatory hormones and fatty acids chronically duel with insulin, causing a cascade of biochemical interactions resulting in insulin resistance, hypertension, and dyslipidemia. Even before beta cells fail and type 2 diabetes ensues, the deadly quartet is quietly rehearsing.