RT Journal Article
SR Electronic
T1 The metabolic syndrome: A tug-of-war with no winner
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 990
OP 994
VO 69
IS 12
A1 Brotman, Daniel J.
A1 Girod, John P.
YR 2002
UL http://www.ccjm.org/content/69/12/990.abstract
AB The metabolic syndrome may be viewed as a state of insulin-counterregulatory overdrive: counterregulatory hormones and fatty acids chronically duel with insulin, causing a cascade of biochemical interactions resulting in insulin resistance, hypertension, and dyslipidemia. Even before beta cells fail and type 2 diabetes ensues, the deadly quartet is quietly rehearsing.