PT  - JOURNAL ARTICLE
AU  - Zanotti, Kristine M.
AU  - Belinson, Jerome
TI  - Update on the diagnosis and treatment of human papillomavirus infection
DP  - 2002 Dec 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 948--961
VI  - 69
IP  - 12
4099  - http://www.ccjm.org/content/69/12/948.short
4100  - http://www.ccjm.org/content/69/12/948.full
SO  - Cleve Clin J Med2002 Dec 01; 69
AB  - Human papillomaviruses (HPVs) are associated with a spectrum of diseases, ranging from common warts to invasive carcinoma of the genital tract. The clinical manifestations of HPV infection depend on the viral subtype, the immune status of the patient, and environmental co-carcinogens. Infection with HPV is often asymptomatic, which makes viral detection challenging. Current therapies do not reliably eradicate HPV infection, and benign genital warts and genital tract intraepithelial neoplasia often recur after treatment. We discuss the pathogenesis, clinical manifestations, detection, and treatment of HPV infections of the anogenital tract.