PT - JOURNAL ARTICLE AU - Andrew S. Zeft AU - Steven J. Spalding TI - Autoinflammatory syndromes: Fever is not always a sign of infection AID - 10.3949/ccjm.79a.11184 DP - 2012 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 569--581 VI - 79 IP - 8 4099 - http://www.ccjm.org/content/79/8/569.short 4100 - http://www.ccjm.org/content/79/8/569.full SO - Cleve Clin J Med2012 Aug 01; 79 AB - Autoinflammatory syndromes are a newly understood group of conditions characterized by recurrent episodes of fever, rash, and serositis. Generalists and specialists should know about and consider these syndromes in the differential diagnosis of recurrent fever. This article reviews the genetics, pathophysiology, clinical presentation, and treatment of several of these relatively recently discovered diseases.