PT - JOURNAL ARTICLE AU - Lee, Pyng AU - Gildea, Thomas R. AU - Stoller, James K. TI - Emphysema in nonsmokers: Alpha 1-antitrypsin deficiency and other causes DP - 2002 Dec 01 TA - Cleveland Clinic Journal of Medicine PG - 928--946 VI - 69 IP - 12 4099 - http://www.ccjm.org/content/69/12/928.short 4100 - http://www.ccjm.org/content/69/12/928.full SO - Cleve Clin J Med2002 Dec 01; 69 AB - Nonsmokers with signs of emphysema at an earlier age than is typical for emphysema deserve a workup for one of the less common causes of emphysema, which include alpha 1-antitrypsin deficiency, connective tissue diseases, hypocomplementemic urticarial vasculitis syndrome, intravenous drug use, human immunodeficiency virus infection, and several rare metabolic disorders.