PT  - JOURNAL ARTICLE
AU  - Fennerty, M. Brian
TI  - The continuum of GERD complications
DP  - 2003 Nov 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S33--S50
VI  - 70
IP  - 11 suppl 5
4099  - http://www.ccjm.org/content/70/11_suppl_5/S33.short
4100  - http://www.ccjm.org/content/70/11_suppl_5/S33.full
SO  - Cleve Clin J Med2003 Nov 01; 70
AB  - Complications of chronic gastroesophageal reflux disease (GERD) run the gamut from erosive esophagitis to esophageal cancer, but all are linked to repeated exposure of the esophagus to caustic gastric and duodenal acid. Progression from one complication to another is not clearly established across the GERD continuum, although there is a clear progression from the serious complication of Barrett’s esophagus to esophageal adenocarcinoma. This review examines the range of complications that can arise from chronic GERD, underscoring the need to view heartburn as a symptom of a potentially serious condition.