PT - JOURNAL ARTICLE ED - Vidt, Donald G. ED - Bakst, Alan AU - Emmanuel L. Bravo TI - Primary aldosteronism: new approaches to diagnosis and management DP - 1993 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 379--386 VI - 60 IP - 5 4099 - http://www.ccjm.org/content/60/5/379.short 4100 - http://www.ccjm.org/content/60/5/379.full SO - Cleve Clin J Med1993 Sep 01; 60 AB - Primary aldosteronism remains a diagnostic challenge. Certain immunoassay techniques, simplified diagnostic testing, and the introduction of sensitive imaging techniques have facilitated the diagnosis, but obstacles that remain include a lack of optimal screening methods, low sensitivity and specificity of current diagnostic tests, and a growing number of etiological subgroups. A rational approach to the diagnosis of primary aldosteronism is described, as is the differentiation of the surgically correctable lesion (adenoma) from the other etiological subgroups.