PT - JOURNAL ARTICLE AU - Lara Jehi TI - Sudden death in epilepsy, surgery, and seizure outcomes: The interface between heart and brain AID - 10.3949/ccjm.77.s3.09 DP - 2010 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - S51--S55 VI - 77 IP - 7 suppl 3 4099 - http://www.ccjm.org/content/77/7_suppl_3/S51.short 4100 - http://www.ccjm.org/content/77/7_suppl_3/S51.full SO - Cleve Clin J Med2010 Jul 01; 77 AB - A significant body of literature suggests that sudden unexpected death in epilepsy (SUDEP) has a cardiac mechanism. Although a correlation has been established between freedom from seizures and reduced SUDEP risk, the exact relationship between seizure outcomes following epilepsy surgery and SUDEP is still being studied. Emerging evidence suggests that seizure outcomes following epilepsy surgery and risk for SUDEP may both be governed by a common underlying biologic process linked to cardiac changes and autonomic dysregulation.