PT - JOURNAL ARTICLE AU - Overmoyer, Beth A. TI - The Breast Cancer Prevention Trial (P-1 Study) DP - 1999 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 33--40 VI - 66 IP - 1 4099 - http://www.ccjm.org/content/66/1/33.short 4100 - http://www.ccjm.org/content/66/1/33.full SO - Cleve Clin J Med1999 Jan 01; 66 AB - The recently completed Breast Cancer Prevention Trial found that tamoxifen can reduce the incidence of breast cancer by nearly half in women at high risk, but the benefit comes at a price of increased risk of endometrial cancer and thromboembolism. This article reviews the actions of tamoxifen and the design, findings, and implications of this study.