PT - JOURNAL ARTICLE AU - Mossad, Sherif B. TI - Underused options for preventing and treating influenza DP - 1999 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 19--23 VI - 66 IP - 1 4099 - http://www.ccjm.org/content/66/1/19.short 4100 - http://www.ccjm.org/content/66/1/19.full SO - Cleve Clin J Med1999 Jan 01; 66 AB - Both amantadine and rimantadine are effective for preventing and treating influenza A, particularly in high-risk patients. However, they should be used judiciously due to the risk of central nervous system side effects and drug interactions. Zanamivir, a new agent for treating influenza, offers promise but needs further study and approval by the Food and Drug Administration before it can be recommended for routine use. Influenza vaccine, the most effective preventive measure, is widely underused.