PT - JOURNAL ARTICLE AU - Ballas, Samir K. TI - Complications of sickle cell anemia in adults: Guidelines for effective management DP - 1999 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 48--58 VI - 66 IP - 1 4099 - http://www.ccjm.org/content/66/1/48.short 4100 - http://www.ccjm.org/content/66/1/48.full SO - Cleve Clin J Med1999 Jan 01; 66 AB - Thanks to improved treatment, most patients with sickle cell disease now survive long into adulthood, but they still face a lifetime of complications and crises, including chronic hemolytic anemia, vascular occlusions, pain, and the side effects of therapy. This article consists of guidelines for diagnosing and treating problems encountered in adult patients with sickle cell disease.