RT Journal Article SR Electronic T1 Complications of sickle cell anemia in adults: Guidelines for effective management JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 48 OP 58 VO 66 IS 1 A1 Ballas, Samir K. YR 1999 UL http://www.ccjm.org/content/66/1/48.abstract AB Thanks to improved treatment, most patients with sickle cell disease now survive long into adulthood, but they still face a lifetime of complications and crises, including chronic hemolytic anemia, vascular occlusions, pain, and the side effects of therapy. This article consists of guidelines for diagnosing and treating problems encountered in adult patients with sickle cell disease.