RT Journal Article SR Electronic T1 United Kingdom Prospective Diabetes Study (UKPDS) JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 247 OP 253 VO 66 IS 4 A1 Christian E. Nasr A1 Byron J. Hoogwerf A1 Charles Faiman A1 S. Sethu K. Reddy YR 1999 UL http://www.ccjm.org/content/66/4/247.abstract AB The United Kingdom Prospective Diabetes Study (UKPDS) showed that intensive treatment (ie, glucose-lowering drugs, with a goal fasting blood glucose level of 108 mg/dL) decreases the microvascular complications of type 2 diabetes mellitus. We summarize the key study results and their implications for clinical management of type 2 diabetes mellitus.