RT Journal Article SR Electronic T1 AIDS update 1999: Viral reservoirs and immune-based therapies JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 267 OP 269 VO 66 IS 5 A2 William S. Wilke A1 Carlos M. Isada A1 Leonard H. Calabrese YR 1999 UL http://www.ccjm.org/content/66/5/267.abstract AB The advent of highly active antiretroviral therapy (HAART) has brought about a dramatic decline in opportunistic infections, hospitalizations, and mortality in AIDS patients. However, the recent discovery that HIV can lay dormant in quiescent T cells and other tissues even in the face of HAART therapy has dampened optimism for a cure for AIDS, though it suggests new avenues of research.