PT  - JOURNAL ARTICLE
ED  - Vidt, Donald G.
AU  - Moreland, Larry W.
TI  - Inhibitors of tumor necrosis factor: New treatment options for rheumatoid arthritis
DP  - 1999 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 367--374
VI  - 66
IP  - 6
4099  - http://www.ccjm.org/content/66/6/367.short
4100  - http://www.ccjm.org/content/66/6/367.full
SO  - Cleve Clin J Med1999 Jun 01; 66
AB  - Infliximab and etanercept, both approved by the FDA in 1998, are examples of a new class of disease-modifying antirheumatic drugs that interfere with the action of tumor necrosis factor alpha, one of the key cytokines that promote inflammation. Infliximab is approved for Crohn disease and etanercept for rheumatoid arthritis. Both show promise in treating rheumatoid arthritis, although the long-term risks and benefits of these drugs are not yet known.