PT - JOURNAL ARTICLE ED - Wilke, William S. AU - Hirschowitz, Basil I. TI - Minimizing the risk of NSAID-induced GI bleeding DP - 1999 Oct 01 TA - Cleveland Clinic Journal of Medicine PG - 524--527 VI - 66 IP - 9 4099 - http://www.ccjm.org/content/66/9/524.short 4100 - http://www.ccjm.org/content/66/9/524.full SO - Cleve Clin J Med1999 Oct 01; 66 AB - Although nonsteroidal anti-inflammatory drugs (NSAIDs) have definite indications and can offer relief for many conditions, many patients have severe gastrointestinal problems after taking them. Physicians should prescribe these drugs more selectively and advise patients to limit their use of over-the-counter NSAIDs. For patients at high risk who need an NSAID, a prophylactic drug or a cydooxygenase 2-selective NSAID can decrease the risk.