RT Journal Article
SR Electronic
T1 The pathogenesis and spectrum of acute coronary syndromes: From plaque formation to thrombosis
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 561
OP 571
VO 66
IS 9
A2 Francis, Gary S.
A1 Patel, Vasant B.
A1 Topol, Eric J.
YR 1999
UL http://www.ccjm.org/content/66/9/561.abstract
AB Acute coronary syndromes occur when an unstable atherosclerotic plaque erodes or ruptures, exposing the highly thrombogenic material inside the plaque to the circulating blood and triggering rapid formation of a thrombus that occludes the artery. This understanding is leading to a wide variety of new therapies. It is hoped that further research into the pathogenesis of acute coronary syndromes will lead to more accurate markers of risk and more specific preventions and treatments.