RT Journal Article
SR Electronic
T1 Stereotactic biopsy of nonneoplastic lesions in adults
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 48
OP 55
VO 59
IS 1
A1 Whiting, Donald M.
A1 Barnett, Gene H.
A1 Estes, Melinda L.
A1 Sila, Cathy A.
A1 Rudick, Richard A.
A1 Hassenbusch, Samuel J.
A1 Lanzieri, Charles F.
YR 1992
UL http://www.ccjm.org/content/59/1/48.abstract
AB Stereotactic biopsy of intracranial lesions has been used primarily for the diagnosis of neoplastic lesions. A series of 158 consecutive stereotactic biopsies performed at The Cleveland Clinic Foundation resulted in 28 diagnoses of non-neoplastic disorders (18%). The majority of these were infectious, inflammatory, or demyelinating disorders. Stereotactic biopsy alone was diagnostic in 17 cases (61%), and biopsy in conjunction with clinical and laboratory data established definitive diagnoses in six cases (22%). All 23 definitive diagnoses led to modifications in patient management. Permanent neurologic morbidity occurred in only two patients (7%). We maintain that this procedure is underused. Stereotactic biopsy is safe, accurate, and useful for diagnosis of non-neoplastic neurologic disorders when the diagnosis is unclear by conventional means. In such cases, its use can lead to early diagnosis and treatment.