PT - JOURNAL ARTICLE AU - Richard A. Rudick AU - Donald E. Goodkin AU - Richard M. Ransohoff TI - Pharmacotherapy of multiple sclerosis: current status DP - 1992 May 01 TA - Cleveland Clinic Journal of Medicine PG - 267--277 VI - 59 IP - 3 4099 - http://www.ccjm.org/content/59/3/267.short 4100 - http://www.ccjm.org/content/59/3/267.full SO - Cleve Clin J Med1992 May 01; 59 AB - Pharmacotherapy plays an important part in the overall management of patients with multiple sclerosis. Most therapies directed at altering the natural history of the underlying disease process are only partially effective or are controversial or experimental. However, many effective symptomatic therapies are available to the clinician. The action and uses of corticosteroids in multiple sclerosis are discussed, and approaches to the treatment of spasticity, paroxysmal disorders, bladder dysfunction, cerebellar ataxia, neurobehavioral manifestations, fatigue, and acute and chronic pain in patients with multiple sclerosis are examined.