RT Journal Article SR Electronic T1 Pharmacotherapy of multiple sclerosis: current status JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 267 OP 277 VO 59 IS 3 A1 Richard A. Rudick A1 Donald E. Goodkin A1 Richard M. Ransohoff YR 1992 UL http://www.ccjm.org/content/59/3/267.abstract AB Pharmacotherapy plays an important part in the overall management of patients with multiple sclerosis. Most therapies directed at altering the natural history of the underlying disease process are only partially effective or are controversial or experimental. However, many effective symptomatic therapies are available to the clinician. The action and uses of corticosteroids in multiple sclerosis are discussed, and approaches to the treatment of spasticity, paroxysmal disorders, bladder dysfunction, cerebellar ataxia, neurobehavioral manifestations, fatigue, and acute and chronic pain in patients with multiple sclerosis are examined.