RT Journal Article SR Electronic T1 Lung and heart-lung transplantation: the state of the art JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 307 OP 316 VO 59 IS 3 A1 Patrick M. McCarthy A1 Thomas J. Kirby A1 Richard D. White A1 Thomas W. Rice A1 Eliot R. Rosenkranz A1 Andrea P. Baldyga A1 Rita Vargo A1 Atul C. Mehta YR 1992 UL http://www.ccjm.org/content/59/3/307.abstract AB Lung and heart-lung transplantation is one of the most rapidly evolving transplantation fields. Survival has been improving with better patient selection, better graft preservation, and better immunosuppression. This paper outlines criteria for patient selection, reviews the surgical options involving lung transplantation, and discusses factors influencing morbidity and survival in these patients. The Cleveland Clinic Foundation experience with these procedures is presented. Lung and heart-lung transplantation has emerged from the experimental realm to the therapeutic, and can now be offered as an effective treatment option to many patients with previously fatal heart and lung disorders.