RT Journal Article
SR Electronic
T1 Circulating lipid and lipoprotein concentrations with oral estrogen-androgen hormone replacement therapy
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 357
OP 358
VO 59
IS 4
A1 David D. Youngs
A1 Byron J. Hoogwerf
A1 Leslie R. Schover
A1 Ruth K. Cannata
YR 1992
UL http://www.ccjm.org/content/59/4/357.abstract
AB The goal of this study was to determine whether the administration of an oral combined estrogen-androgen preparation would influence the lipid and lipoprotein profile of postmenopausal women. There were no pretreatment to posttreatment differences in triglycerides, total cholesterol, or in low density lipoproteins and very low density lipoproteins. However, high density lipoprotein values decreased significantly after treatment. Although further study is warranted, these preliminary findings suggest that the potential beneficial effects of oral estrogen-androgen on sexual and psychological well-being may need to be weighed against the possible cardiovascular risks of adverse lipid changes in postmenopausal women.