RT Journal Article
SR Electronic
T1 Nontraditional combination pharmacotherapy of hypertension
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 459
OP 468
VO 59
IS 5
A1 Sutton, James M.
A1 Bagby, Susan P.
YR 1992
UL http://www.ccjm.org/content/59/5/459.abstract
AB Traditional drug combinations that have additive hypotensive effect include double therapy with a diuretic and any other antihypertensive agent and triple therapy with a diuretic, direct vasodilator, and either a beta blocker or reserpine. Due to the availability of new classes of antihypertensive agents, other combinations of drugs are now increasingly used. The effectiveness of combination therapy for hypertension has been investigated; the results of these studies are reviewed.