RT Journal Article SR Electronic T1 Suicide risk associated with drug and alcohol addiction JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 535 OP 538 VO 59 IS 5 A1 Norman S. Miller A1 A. James Giannini A1 Mark S. Gold YR 1992 UL http://www.ccjm.org/content/59/5/535.abstract AB The association of alcohol and drugs with suicidal thinking and behavior is both causal and conducive. The subjective state of hopelessness is key to the disposition to actual suicide. Alcohol and drugs are influential in providing a feeling of hopelessness by their toxic effects, by disruption of interpersonal relationships and social supports, and, possibly, by manipulating neurotransmitters responsible for mood and judgment. Because alcoholism and drug addiction are leading risk factors for suicide and suicidal behavior, any alcoholic or drug addict should be assessed for suicide, especially if actively using alcohol or drugs.