PT - JOURNAL ARTICLE AU - Moodie, Douglas S. AU - Hanhan, Usama AU - Sterba, Richard AU - Murphy, Daniel J. AU - Rosenkranz, Eliot R. AU - Kovacs, Andrea M. TI - Aortic valve replacement in young patients: long-term follow-up DP - 1992 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 473--478 VI - 59 IP - 5 4099 - http://www.ccjm.org/content/59/5/473.short 4100 - http://www.ccjm.org/content/59/5/473.full SO - Cleve Clin J Med1992 Sep 01; 59 AB - Thirty-four young patients (28 male and 6 female) underwent aortic valve replacement between 1972 and 1988. Ages ranged from 11 to 20 years (mean 17.7 years). Including reimplantation in the follow-up period, 40 valves were implanted, among which were 17 (43%) St. Jude, 7 (16%) Bjork-Shiley, and 4 (10%) Carpentier-Edwards. Seven patients (18%) had tissue valve prostheses (4 Carpentier-Edwards, 3 Hancock valves). There was one hospital death (2.9%). Follow-up was obtained in 30 of the 33 hospital survivors, with a mean follow-up of 80 months. In the follow-up period, one patient (3%) had a major thromboembolic event and one patient (3%) had prosthetic valve endocarditis. Six patients (18%) required replacement of the implanted valve; three of these had received Hancock tissue valve prostheses. There were three late deaths, yielding 96% survival at 5 years and 84% at 10 years. Twenty-three of 30 survivors are currently New York Heart Association class I. Aortic valve replacement in young patients can be performed with low mortality and morbidity, and with excellent long-term results.