PT  - JOURNAL ARTICLE
AU  - Olin, Jeffrey W.
AU  - Cressman, Michael D.
AU  - Young, Jess R.
AU  - Hoogwerf, Byron J.
AU  - Weinstein, Cheryl E.
TI  - Lipid and lipoprotein abnormalities in lower-extremity arteriosclerosis obliterans
DP  - 1992 Sep 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 491--497
VI  - 59
IP  - 5
4099  - http://www.ccjm.org/content/59/5/491.short
4100  - http://www.ccjm.org/content/59/5/491.full
SO  - Cleve Clin J Med1992 Sep 01; 59
AB  - The prevalence of abnormal lipid and lipoprotein values was determined in 125 consecutive patients with lower-extremity arteriosclerosis obliterans, and the lipid and lipoprotein abnormalities in these patients were characterized. Only 13% of the patients had normal lipid/lipoprotein profiles. Forty-eight percent of patients had low levels of high-density lipoprotein cholesterol. High-density lipoprotein cholesterol values were lower in patients with concomitant coronary heart disease compared with those without heart disease. High-density lipoprotein cholesterol values were inversely related to weight, to triglyceride values, and to diabetes mellitus. Twenty-eight percent of patients had "desirable" total cholesterol levels (<200 mg/dL), and 32% had low-density lipoprotein cholesterol values less than 130 mg/dL. Following National Cholesterol Education Program guidelines may be misleading in patients with documented lower-extremity atherosclerosis; therefore, complete lipid/lipoprotein profiles should be performed in these patients.