RT Journal Article
SR Electronic
T1 Lipid and lipoprotein abnormalities in lower-extremity arteriosclerosis obliterans
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 491
OP 497
VO 59
IS 5
A1 Olin, Jeffrey W.
A1 Cressman, Michael D.
A1 Young, Jess R.
A1 Hoogwerf, Byron J.
A1 Weinstein, Cheryl E.
YR 1992
UL http://www.ccjm.org/content/59/5/491.abstract
AB The prevalence of abnormal lipid and lipoprotein values was determined in 125 consecutive patients with lower-extremity arteriosclerosis obliterans, and the lipid and lipoprotein abnormalities in these patients were characterized. Only 13% of the patients had normal lipid/lipoprotein profiles. Forty-eight percent of patients had low levels of high-density lipoprotein cholesterol. High-density lipoprotein cholesterol values were lower in patients with concomitant coronary heart disease compared with those without heart disease. High-density lipoprotein cholesterol values were inversely related to weight, to triglyceride values, and to diabetes mellitus. Twenty-eight percent of patients had "desirable" total cholesterol levels (<200 mg/dL), and 32% had low-density lipoprotein cholesterol values less than 130 mg/dL. Following National Cholesterol Education Program guidelines may be misleading in patients with documented lower-extremity atherosclerosis; therefore, complete lipid/lipoprotein profiles should be performed in these patients.