RT Journal Article
SR Electronic
T1 Adjuvant therapy for colorectal cancer
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 603
OP 607
VO 59
IS 6
A1 Vernava, Anthony M.
YR 1992
UL http://www.ccjm.org/content/59/6/603.abstract
AB The search for effective adjuvant therapy for colorectal cancer has been long and, until recently, largely unrewarding. Surgery alone is inadequate therapy in as many as 5 0 % of patients. But recent studies demonstrate significant improvement in disease-free survival and overall survival for patients with advanced colon and rectal cancer who receive adjuvant therapy. Postoperative chemotherapy with fluorouracil and levamisole is the standard of care for patients with stage III colon cancer, and postoperative high-dose pelvic radiation combined with fluorouracil is the standard regimen for patients with stage II and III rectal cancer.