PT - JOURNAL ARTICLE AU - Gabbard, Scott AU - Vijayvargiya, Sonya TI - Functional heartburn: An underrecognized cause of PPI-refractory symptoms AID - 10.3949/ccjm.86a.19006 DP - 2019 Dec 01 TA - Cleveland Clinic Journal of Medicine PG - 799--806 VI - 86 IP - 12 4099 - http://www.ccjm.org/content/86/12/799.short 4100 - http://www.ccjm.org/content/86/12/799.full SO - Cleve Clin J Med2019 Dec 01; 86 AB - Functional heartburn—persistent symptoms of esophageal reflux with no objective evidence of gastroesophageal reflux disease (GERD)—is the most common cause of failure of proton pump inhibitor (PPI) therapy, but it is often overlooked by internists and gastroenterologists.