TY - JOUR T1 - Functional heartburn: An underrecognized cause of PPI-refractory symptoms JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 799 LP - 806 DO - 10.3949/ccjm.86a.19006 VL - 86 IS - 12 AU - Scott Gabbard AU - Sonya Vijayvargiya Y1 - 2019/12/01 UR - http://www.ccjm.org/content/86/12/799.abstract N2 - Functional heartburn—persistent symptoms of esophageal reflux with no objective evidence of gastroesophageal reflux disease (GERD)—is the most common cause of failure of proton pump inhibitor (PPI) therapy, but it is often overlooked by internists and gastroenterologists. ER -