RT Journal Article SR Electronic T1 Fixed drug eruption from pamabrom JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 33 OP 34 VO 58 IS 1 A1 Nedorost, Susan A1 Taylor, James S. A1 Camisa, Charles A1 Tomecki, Kenneth J. A1 Helm, Thomas A1 Durkin, William J. YR 1991 UL http://www.ccjm.org/content/58/1/33.abstract AB A young woman presented with recurrent skin lesions that were predominantly perioral. Fixed drug reaction was diagnosed based on her history of intermittent ingestion of Pamprin, a common menstrual symptom reliever, and characteristic erythematous, pigmented, edematous patches. After oral challenge with two of the three ingredients in Pamprin, a diagnosis of fixed drug reaction to pamabrom was made. Pamabrom is a mild diuretic present in several over-the-counter and prescription menstrual symptom relievers. This is the first reported case of fixed drug reaction to pamabrom.