PT  - JOURNAL ARTICLE
ED  - Brouhard, Ben H.
AU  - Bretan, Peter N.
AU  - Novick, Andrew C.
TI  - A new intracellular flush solution improves renal transplant preservation
DP  - 1991 Jan 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 54--58
VI  - 58
IP  - 1
4099  - http://www.ccjm.org/content/58/1/54.short
4100  - http://www.ccjm.org/content/58/1/54.full
SO  - Cleve Clin J Med1991 Jan 01; 58
AB  - A new renal preservation flush solution (PB-2) has been developed to minimize the ischemic injury processes that occur during hypothermic storage and reperfusion and that can decrease renal viability and survival. Development of the new formulation took into account the intracellular and biological interactions that occur pre- and post-transplantation. PB-2 was compared with the conventional standardized Collins-2 flush solution in the preservation of autografts in dogs and was found to provide significantly improved renal recovery, viability, and survival. Studies to test the new solution in human renal allograft transplant preservation are planned.