RT Journal Article SR Electronic T1 Tailoring antihypertensive therapy in 1991 JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 277 OP 284 VO 58 IS 3 A2 Donald G. Vidt A2 Alan Bakst YR 1991 UL http://www.ccjm.org/content/58/3/277.abstract AB Tailored care will increasingly become the hallmark of treatment for patients with hypertension in the 1990s. In mildly hypertensive patients, treatment should begin with nonpharmacologic approaches to lower blood pressure and reduce the patient’s cardiovascular risk profile. The ever-increasing array of antihypertensive drugs and drug classes will enable clinicians to select agents based on the advantages and disadvantages for a particular patient, while continuing to move away from the rigid guidelines of stepped care. Physicians more often will base their choice of antihypertensive therapy not on safety and efficacy alone, but rather on the safety and efficacy of the drug in long-term care and the impact of therapy on quality of life.